Challenges In Cartilage Tissue Engineering
نویسندگان
چکیده
منابع مشابه
Challenges in Cartilage Tissue Engineering
Over 27 million Americans suffer from cartilage damage with several million people affected per year. Articular cartilage or hyaline cartilage has a limited capacity to heal after damage from injury or degenerative disease. In an attempt to delay the progression of widespread damage, orthopedic surgeons routinely treat osteochondral injuries with minimally invasive surgical procedures involving...
متن کاملCartilage tissue engineering: current scenario and challenges
Cartilage is an avascular connective tissue found in many locations in the body, such as, in the joints between the bones, rib cage, ear, nose and intervertebral discs. Cartilage plays a vital role in our body by working as a cushion between joints so that rubbing of bones against each other is prevented. It also holds some bones together, for instance, rib cartilage, and makes the area shock-p...
متن کاملImportance of Floating Chondrons in Cartilage Tissue Engineering
BACKGROUND Dedifferentiation of chondrocytes remains a major problem for cartilage tissue engineering. Chondrocytes loss differentiated phenotype in in vitro culture that is undesired for repair strategies. The chondrocyte is surrounded by a pericellular matrix (PCM), together forming the chondron. PCM has a positive effect on the maintenance of chondrocyte phenotype during culture in compar...
متن کاملEngineering cartilage tissue.
Cartilage tissue engineering is emerging as a technique for the regeneration of cartilage tissue damaged due to disease or trauma. Since cartilage lacks regenerative capabilities, it is essential to develop approaches that deliver the appropriate cells, biomaterials, and signaling factors to the defect site. The objective of this review is to discuss the approaches that have been taken in this ...
متن کاملTissue engineering of cartilage
The main goal of tissue engineering is to create artificial constructs that could repair or simply replace lost or damaged tissue. Common tissue engineering strategies involve the extraction of cells from a small biopsy of tissue for in vitro expansion. This culture can be carried out in a three dimensional (3D) scaffold that allows and induces the formation of new tissue after implantation. Fu...
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ژورنال
عنوان ژورنال: Journal of Tissue Science & Engineering
سال: 2013
ISSN: 2157-7552
DOI: 10.4172/2157-7552.1000e120